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Title Randomised response-adaptive designs in clinical trials / Anthony C. Atkinson, Atanu Biswas.
Imprint Boca Raton, FL : CRC Press, [2013]


 Internet  Electronic Book    AVAILABLE
Description 1 online resource (xv, 336 pages) : illustrations
Series Chapman & Hall/CRC Monographs on Statistics & Applied Probability
Chapman & Hall/CRC Monographs on Statistics & Applied Probability.
Note Available only to authorized UTEP users.
Print version record.
Subject Clinical trials -- Statistical methods.
Clinical Trials as Topic -- methods.
Statistics -- methods
Contents Front Cover; Contents; Preface; 0. Introduction: Stories and Data; 1. Adaptive Design: Controversies and Progress; 2. Randomised Balanced Sequential Treatment Allocation; 3. Response-Adaptive Designs for Binary Responses; 4. Response-Adaptive Designs for Continuous Responses; 5. Response-Adaptive Designs for Longitudinal Responses; 6. Optimum Biased-Coin Designs with Covariates; 7. Optimum Response-Adaptive Designs with Covariates; 8. Optimal Response-Adaptive Designs with Constraints; 9. Adaptive Design: Further Important Issues; A. Optimum Design.
Summary Randomised Response-Adaptive Designs in Clinical Trials presents methods for the randomised allocation of treatments to patients in sequential clinical trials. Emphasizing the practical application of clinical trial designs, the book is designed for medical and applied statisticians, clinicians, and statisticians in training. After introducing clinical trials in drug development, the authors assess a simple adaptive design for binary responses without covariates. They discuss randomisation and covariate balance in normally distributed responses and cover many.
Other Author Biswas, Atanu, author.
Other Title Print version: Atkinson, Anthony C. Randomised Response-Adaptive Designs in Clinical Trials. Hoboken : Taylor and Francis, ©2013 9781584886938