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Title Design and analysis of animal studies in pharmaceutical development / edited by Shein-Chung Chow, Jen-pei Liu.
Imprint New York, N.Y. : Marcel Dekker, 1998.


 Internet  Electronic Book    AVAILABLE
Description 1 online resource (x, 407 pages) : illustrations
Series Biostatistics (New York, N.Y.) ; 1.
Bibliog. Includes bibliographical references and index.
Note Available only to authorized UTEP users.
Print version record.
Subject Pharmacy -- Research -- Statistical methods.
Diseases -- Animal models.
Laboratory animals.
Drug Evaluation, Preclinical -- methods.
Animals, Laboratory.
Statistics as Topic -- methods.
Toxicity Tests -- methods.
Contents Cover -- Half Title -- Title Page -- Copyright Page -- Contents -- Series Introduction -- Preface -- Contributors -- 1. Introduction -- 2. Experimental Design Principles for Animal Studies in Pharmaceutical Development -- 3. Interval Estimation with Small Samples for Median Lethal Dose or Median Effective Dose -- 4. Principles in Statistical Testing in Randomized Toxicological Studies -- 5. Subchronic Toxicity Studies -- 6. Safety Assessment in Toxicological Studies: Proof of Safety Versus Proof of Hazard -- 7. The Design of Long-Term Carcinogenicity Studies -- 8. Analysis of Long-Term Carcinogenicity Studies -- 9. Design of Developmental and Reproductive Toxicology Studies -- 10. Analysis of Reproductive and Developmental Studies -- 11. The In Vitro Ames Tests -- 12. The In Vitro Chinese Hamster Ovary Cell Mutagenesis Studies -- Index.
Other Author Chow, Shein-Chung, 1955-
Liu, Jen-pei, 1952-
Other Title Print version: Design and analysis of animal studies in pharmaceutical development. New York, N.Y. : Marcel Dekker, 1998 0824701305