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Title Biosimulation in biomedical research, health care and drug development / Erik Mosekilde, Olga Sosnovtseva, Amin Rostami-Hodjegan, editors.
Imprint Vienna ; New York : SpringerWienNewYork, ©2012.


 Internet  Electronic Book    AVAILABLE
Description 1 online resource (xv, 396 pages)
Bibliog. Includes bibliographical references and index.
Note Available only to authorized UTEP users.
Subject Medicine -- Research -- Simulation methods.
Biology -- Research -- Simulation methods.
Drug development -- Simulation methods.
Systems biology.
Biomedical Research.
Computer Simulation.
Drug Design.
Drug Therapy.
Models, Biological.
life sciences
toegepaste statistiek
applied statistics
public health
computational science
biomedische wetenschappen
Medicine (General)
Geneeskunde (algemeen)
Summary Biosimulation is an approach to biomedical research and the treatment of patients in which computer modeling goes hand in hand with experimental and clinical work. Constructed models are used to interpret experimental results and to accumulate information from experiment to experiment. The book explains the concepts used in the modeling of biological phenomena and goes on to present a series of well-documented models of the regulation of various cellular and physiological processes, emphasizing particularly the role of self-sustained biological activity. The way how the use of computer models allows optimization of the treatment of various diseases for individual patients is discussed and models of interacting nerve cells that can be used to design new treatments for patients with Parkinson's disease are explained. Furthermore this volume provides a discussion of the use of models in the pharmaceutical industry, and presents the view of the regulatory agencies on the topic.
Other Author Mosekilde, Erik.
Sosnovtseva, Olga.
Rostami-Hodjegan, Amin.
Other Title Print version: Biosimulation in biomedical research, health care and drug development. Vienna ; New York : SpringerWienNewYork, ©2012