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Title Medication development for the treatment of cocaine dependence : issues in clinical efficacy trials / editors, Betty Tai, Nora Chiang, Peter Bridge.
Imprint Rockville, MD : U.S. Dept. of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Office of Science Policy and Communications ; [Washington, D.C. : Supt. of Docs., U.S. G.P.O., distributor], 1997.

Copies/Volumes

LOCATION CALL # STATUS
 GovDocs Federal  HE 20.3965:175    AVAILABLE
Description iv, 329 p. : ill. ; 24 cm.
Series NIDA research monograph ; 175.
NIH publication ; no. 98-4125.
Note "Based on the papers from a technical review ... held on October 20-21, 1994"--p. ii.
Shipping list no.: 98-0092-P.
Bibliog. Includes bibliographical references.
Subject Cocaine abuse -- Chemotherapy -- Congresses.
Cocaine abuse -- Treatment -- Congresses.
Clinical trials -- Congresses.
Cocaine -- Congresses.
Substance-Related Disorders -- drug therapy -- Congresses.
Substance Abuse Detection -- Congresses.
Drug Evaluation -- Congresses.
Clinical Trials as Topic -- Congresses.
Contents Goals and rationale for pharmacotherapeutic approach in treating cocaine dependence: insights from basic and clinical research -- Overview of potential treatment medications for cocaine dependence -- Methodologic recommendations for cocaine abuse clinical trials: a clinician-researcher's perspective -- Management of clinical trials with new medications for cocaine dependence and abuse -- Outcome measurement considerations: pharmacological treatments for substance abuse -- Variability in treatment-seeking cocaine abusers: implications for clinical pharmacotherapy trials --Baseline assessment, study entry, and stabilization: double-blind clinical trials in drug dependence -- Addiction severity index in clinical efficacy trials of medications for cocaine dependence -- Cognitive-neuromotor assessment of substance abuse: focus on issues related to cocaine abuse treatment -- Treatment effectiveness score as an outcome measure in clinical trials -- Pharmacokinetics of cocaine: considerations when assessing cocaine use by urinalysis -- Quantitative urine levels of cocaine and other substances of abuse -- Use of quantitative urinalysis in monitoring cocaine use -- Is quantitative urinalysis more sensitive? -- Comparison of immunoassays for semiquantitative measurement of benzoylecgonine in urine -- Appendix I: Workshop summary outcome measures and success criteria -- Appendix II: Workshop summary clinical decision tree for cocaine addiction pharmacotherapy.
Other Author Tai, Betty.
Chiang, C. Nora.
Bridge, Peter, M.D.
National Institute on Drug Abuse. Office of Science Policy and Communications.