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Title Clinical trials in hypertension / edited by Henry R. Black.
Imprint New York : Marcel Dekker, ©2001.


 Internet  Electronic Book    AVAILABLE
Description 1 online resource (xi, 659 pages) : illustrations, maps
Bibliog. Includes bibliographical references and index.
Note Available only to authorized UTEP users.
Print version record.
Subject Hypertension -- Chemotherapy -- Evaluation -- History.
Hypotensive agents -- Testing -- History.
Clinical trials -- Evaluation -- History.
Hypertension -- drug therapy.
Antihypertensive Agents -- therapeutic use.
Clinical Trials as Topic -- history.
Genre History.
Contents The Veterans Administration Cooperative Study on Antihypertensive Drugs -- The treatment of mild essential hypertension: The U.S. Public Health Service Hospitals Clinical Trial -- The Hypertension Detection and Follow-up Program -- The Australian National Blood Pressure Study 1973-1979 / Ralph Reader -- The MRC Trial of Treatment in Mild Hypertension -- Beta-blockers versus diuretics in hypertensive men: The HAPPHY Trial -- Metoprolol versus thiazide diuretics in hypertension: results from the MAPHY Study in perspective -- The European Working Party on High Blood Pressure in the Elderly (EWPHE) Trial -- The Swedish Trial in Old Patients with Hypertension (STOP-Hypertension) -- Systolic Hypertension in the Elderly Program (SHEP): the first demonstration that lowering systolic hypertension reduced total stroke and all coronary heart disease -- Medical Research Council Trial of Treatment of Hypertension in Older Adults -- The Treatment of Mild Hypertension Study (TOMHS): design and additional analyses.
Department of Veterans Affairs Cooperative Study on Monotherapy of Hypertension -- The Systolic Hypertension in Europe Trial -- Hypertension Optimal Treatment (HOT) Study -- Beta-blocker Heart Attack Trial -- Effect of enalapril on morbid and mortal events among SOLVD participants with hypertension -- Captopril in Type 1 Diabetic Nephropathy -- Attenuation of ventricular enlargement: The SAVE study -- STOP-Hypertensio-2: The Swedish Trial in Old Patients with Hypertension-2 -- The Controlled ONset Verapamil INvestigation of Cardiovascular Endpoints (CONVINCE) Trial -- Rationale and design for the Antihypertensive and Lipid-lowering Treatment to Prevent Heart Attack Trial (ALLHAT) -- The 2nd Australian National Blood Pressure Study (ANBP2) -- Losartan Intervention for Endpoint Reduction in Hypertension: The LIFE Study -- Prospective collaborative overviews of major randomized trials of blood-pressure-lowering treatments.
Summary Compiling descriptions, results, and analyses from 24 complete or soon-to-be-complete influential clinical trials studying the efficacy of pharmacological therapy in hypertension, this detailed reference examines treatment for hypertension from a variety of perspectives, including trials sponsored by both international governments and pharmaceutical firms. Organized to facilitate convenient comparison and evaluation of results for therapeutic decisions, Clinical Trials in Hypertension: identifies objectives, inclusion/exclusion criteria, baseline characteristics of subjects, and drug regimens; spotlights trials that established the effectiveness of breakthrough treatments such as treating young hypertensives with diastolic blood pressure elevations; reviews numerous drug studies-including Heart Attack Primary Prevention in Hypertension (HAPPHY), Metoprolol Atherosclerosis Prevention in Hypertensives (MAPHY), and Treatment of Mild Hypertension Study (TOMHS)-contrasting diuretics, -adrenergic receptor blockers, angiotensin converting enzyme inhibitors, -adrenergic receptor blockers, and calcium antagonists; considers treatment options and results with older hypertensives; and more! Reports on the collaboration between the World Health Organization and the International Society of Hypertension pooling data from more than 30 clinical trials currently in progress.
Other Author Black, Henry R. (Henry Richard), 1942-
Other Title Print version: Clinical trials in hypertension. New York : Marcel Dekker, ©2001 0824702700