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Title Handbook of adaptive designs in pharmaceutical and clinical development / edited by Annpey Pong, Shein-Chung Chow.
Imprint Boca Raton, FL : CRC Press, c2011.


 Main Stacks  R853.C55 H355 2011    AVAILABLE
Description 1 v. (various pagings) : ill. ; 27 cm.
Bibliog. Includes bibliographical references and index.
Subject Clinical trials -- Handbooks, manuals, etc.
Drugs -- Research -- Methodology -- Handbooks, manuals, etc.
Summary "This comprehensive guide offers a unified presentation of the principles and methodologies in adaptive design and analysis. It gives a well-balanced summary of current regulatory perspectives and recently developed statistical methods in this area. The handbook provides some insight regarding early phase and later phase adaptive designs. With a focus on the implementation of adaptive methods in clinical trials, it introduces the concepts of role, responsibility, function, and activity of a data safety monitoring board (DSMB) when applying these methods. Other important topics covered in detail include regulatory perspectives and logistics issues in applying adaptive design methods"--Provided by publisher.
Other Author Pong, Annpey.
Chow, Shein-Chung, 1955-