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E-BOOK
Title Randomization, masking, and allocation concealment / edited by Vance Berger.
Imprint Boca Raton : CRC Press, [2018]
©2018

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 Internet  Electronic Book    AVAILABLE
Description 1 online resource (xiii, 251 pages)
Series Chapman & Hall/CRC Biostatistics series
Chapman & Hall/CRC biostatistics series.
Note "A Chapman & Hall book."
Bibliog. Includes bibliographical references and index.
Note Available only to authorized UTEP users.
Description based on print version record.
Subject Clinical trials -- Statistical methods.
Clinical trials -- Moral and ethical aspects.
Contents Chapter 1 Randomization and Bias in Historical Perspective / J. Rosser Matthews -- chapter 2 Proper Randomization Reduces the Chance of Wasted Biomedical Research / Arturo Martí-Carvajal -- chapter 3 Sympathetic Bias: A Neglected Source of Selection Bias / William C. Grant -- chapter 4 The Alleged Benefits of Unrestricted Randomization / Vance W. Berger -- chapter 5 Restricted Randomization: Pros and Cautions / Jonathan Chipman -- chapter 6 Evolution of Restricted Randomization with Maximum Tolerated Imbalance / Wenle Zhao -- chapter 7 Evaluating the Evaluation / Adriana C. Burgos -- chapter 8 Selection Bias in Studies with Unequal Allocation / Olga M. Kuznetsova -- chapter 9 Unrecognized Dual Threats to Internal Validity Relating to Randomization / Vance W. Berger -- chapter 10 Testing for Second-Ordifer Selection Bias Effect in Randomised Controlled Trials Using Reverse Propensity Score (RPS) / Steffen Mickenautsch -- chapter 11 The Berger-Exner Test to Detect Third-Ordifer Selection Bias in the Presence of a True Treatment Effect / Steffen Mickenautsch -- chapter 12 Adjusting for and Detection of Selection Bias in Randomized Controlled Clinical Trials / Lieven N. Kennes -- chapter 13 Randomization and the Randomization Test: Two Sides of the Same Coin / Patrick Onghena -- chapter 14 Randomization Tests or Permutation Tests? A Historical and Terminological Clarification / Patrick Onghena -- chapter 15 Flexible Minimization: Synergistic Solution for Selection Bias / Donald R. Taves.
Summary "Randomization, Masking, and Allocation Concealment is indispensable for any trial researcher who wants to use state of the art randomization methods, and also wants to be able to describe these methods correctly.Far too often the subtle nuances that distinguish proper randomization from flawed randomization are completely ignored in trial reports that state only that randomization was used, with no additional information. Experience has shown that in many cases, the type of randomization that was used was flawed. It is only a matter of time before medical journals and regulatory agencies come to realize that we can no longer rely on (or publish) flawed trials, and that flawed randomization in and of itself disqualifies a trial from being robust or high quality, even if that trial is of high quality otherwise.This book will help to clarify the role randomization plays in ensuring internal validity, and in drawing valid inferences from the data. The various chapters cover a variety of randomization methods, and are not limited to the most common (and most flawed) ones. Readifers will come away with a profound undiferstanding of what constitutes a valid randomization procedure, so that they can distinguish the valid from the flawed among not only existing methods but can also methods yet to be developed. "--Provided by publisher.
Other Author Berger, Vance, editor.