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Title Data monitoring in clinical trials : a case studies approach / David L. DeMets, Curt D. Furberg, Lawrence M. Friedman, editors.
Imprint New York, NY : Springer, ©2006.


 Internet  Electronic Book    AVAILABLE
Description 1 online resource (xxvi, 374 pages) : illustrations
Bibliog. Includes bibliographical references and index.
Note Available only to authorized UTEP users.
Subject Clinical trials -- Data processing.
Clinical trials -- Case studies.
Biomedical Research -- standards.
Randomized Controlled Trials
Clinical Trials Data Monitoring Committees.
Genre Case studies.
Contents Monitoring Committees: Why and How; Lessons Learned; FDA and Clinical Trial Data Monitoring Committees; Introduction to Case Studies Showing Benefit from the Intervention; Assessing Possible Late Treatment Effects Early: The Diabetic Retinopathy Study Experience; Data and Safety Monitoring in the Beta-Blocker Heart Attack Trial: Early Experience in Formal Monitoring Methods; Data Monitoring for the Aspirin Component of the Physicians' Health Study: Issues in Early Termination for a Major Secondary Endpoint.
Summary "This book should be useful to anyone serving on a data and safety monitoring board, or planning to do so, for colleagues in academia, industry and governmental agencies, and for students in biostatistics, epidemiology, clinical trials and medical ethics. No other text has as extensive a collection of cases which provide insight into the many issues, often conflicting, that must be examined before recommendations to continue or discontinue a trial can be made. While depth in statistical methods is not required, some familiarity with statistical design and analysis issues in clinical trials is helpful."--Jacket
Other Author Furberg, Curt.
Friedman, Lawrence M., 1942-
Other Title Springer e-books
Print version: DeMets, David L., 1944- Data monitoring in clinical trials. New York, NY : Springer, ©2006 0387203303