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Title Adaptive and flexible clinical trials / Richard Chin.
Imprint Boca Raton, Fla. : CRC Press, [2012]


 Internet  Electronic Book    AVAILABLE
Description 1 online resource (xiii, 184 pages) : illustrations
Note "A Chapman & Hall book."
Bibliog. Includes bibliographical references and index.
Note Available only to authorized UTEP users.
Print version record.
Subject Clinical trials.
Clinical Trials as Topic.
Database Management Systems -- trends.
Efficiency, Organizational.
Research Design.
Contents 1. Background -- 2. Conventional statistics -- 3. Statistics used in adaptive clinical trials -- 4. Specific requirements for adaptive trials -- 5. Adaptive randomization and allocation -- 6. Sample size reestimation -- 7. Traditional dosing -- 8. Adaptive dosing -- 9. Interim analysis and adaptive termination of study and study arms -- 10. Adaptive changes in study design and decision rules -- 11. Seamless designs and adaptive clinical trial conduct -- 12. Analysis and interpretation of results.
Other Title Print version: Adaptive and Flexible Clinical Trials. CRC Press, LLC, 2011 9781439838327