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Title Molecularly targeted therapy for childhood cancer / Peter J. Houghton, Robert J. Arceci, editors.
Imprint New York : Springer, ©2010.


 Internet  Electronic Book    AVAILABLE
Description 1 online resource (xviii, 536 pages) : illustrations (some color)
Bibliog. Includes bibliographical references and index.
Note Available only to authorized UTEP users.
Print version record.
Subject Cancer in children -- Gene therapy.
Neoplasms -- therapy.
Molecular Targeted Therapy.
Antineoplastic Agents -- pharmacology.
Contents The Emerging Era of Targeted Therapy in Childhood Acute Lymphoblastic Leukemia; Molecular Targeted Therapies in T-CellAcute Lymphoblastic Leukemia; Molecularly Targeted Therapy for Infant ALL; Targeted Therapeutic Approaches for AML; Acute Promyelocytic Leukaemia; Down Syndrome and Acute Myeloid Leukemia: An Unique Genetic Sensitivity to Chemotherapy; Targeting RAS Signaling Pathways in Juvenile Myelomonocytic Leukemia (JMML); Chronic Myeloid Leukemia: Pathophysiology and Therapeutics; Molecularly Targeted Therapies in Pediatric Myelodysplastic Syndromes.
Summary Each chapter will focus on the known molecular characteristics of specific childhood cancers, focusing on how the molecular 'drivers' can be exploited from a therapeutic standpoint with currently available targeted agents. Where applicable, integration of targeted therapies with conventional cytotoxic agents will be considered. This volume will provide a comprehensive summary of molecular characteristics of childhood cancers, and how the changes involved in transformation provide us with opportunities for developing relatively less toxic, but curative, therapies.
Other Author Houghton, Peter J.
Arceci, Robert.
Other Title Springer eBooks
Print version: Molecularly targeted therapy for childhood cancer. New York : Springer, ©2010 9780387690605