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Title A handbook of bioanalysis and drug metabolism / edited by Gary Evans.
Imprint Boca Raton, Fla. : CRC Press, ©2004.


 Internet  Electronic Book    AVAILABLE
Description 1 online resource (xii, 390 pages) : illustrations
Bibliog. Includes bibliographical references and index.
Note Available only to authorized UTEP users.
Print version record.
Subject Drugs -- Analysis.
Drugs -- Metabolism -- Research -- Methodology.
Pharmacokinetics -- Research -- Methodology.
Pharmaceutical Preparations -- metabolism.
Chemistry Techniques, Analytical.
Drug Industry.
Genre Electronic book.
Contents Front cover; Contents; Editor's preface; Preface; Grieves Harnby: In memoriam; 1 Introduction; 2 The importance of the physicochemical properties of drugs to drug metabolism; 3 Sample preparation; 4 High-performance liquid chromatography in pharmaceutical bioanalysis; 5 Mass spectrometry and quantitative bioanalysis; 6 Immunoassay in pharmacokinetic and pharmacodynamic bioanalysis; 7 Pre-clinical pharmacokinetics; 8 Pharmacokinetic/ pharmacodynamic modelling in pre-clinical drug discovery; 9 Toxicokinetics; 10 Protein binding in plasma: a case history of a highly protein-bound drug.
11 Isotope drug studies in man12 Whole body autoradiography; 13 Phase I metabolism; 14 Phase II enzymes; 15 In vitro tecniques for investigating drug metabolism; 16 Drug-drug interactions: an in vitro approach; 17 Identification of drug metabolites in biological fluids using qualitative spectroscopic and chromatographic techniques; 18 Molecular biology; 19 The role of drug metabolism and pharmacokinetics in drug discovery: past, present and future; Index; Back cover.
Summary Recent years have seen a greater industrial emphasis in undergraduate and postgraduate courses in the pharmaceutical and chemical sciences. However, textbooks have been slow to adapt, leaving the field without a text/reference that is both instructional and practical in the industrial setting - until now. A Handbook of Bioanalysis and Drug Metabolismis a stimulating new text that examines the techniques, methodology, and theory of bioanalysis, pharmacokinetics, and metabolism from the perspective of scientists with extensive professional experience in drug discovery and developme.
Other Author Evans, Gary, 1953-
Other Title Print version: Handbook of bioanalysis and drug metabolism. Boca Raton, Fla. : CRC Press, ©2004 0415275199 0415275202