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Title Cancer biomarkers : the promises and challenges of improving detection and treatment / Committee on Developing Biomarker-Based Tools for Cancer Screening, Diagnosis, and Treatment, Institute of Medicine of the National Academies ; Sharyl J. Nass and Harold L. Moses, editors.
Imprint Washington, D.C. : National Academies Press, ©2007.


 Internet  Electronic Book    AVAILABLE
Description 1 online resource (xiv, 236 pages) : illustrations
Bibliog. Includes bibliographical references.
Note Use copy Restrictions unspecified star MiAaHDL
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Reproduction Electronic reproduction. [Place of publication not identified] : HathiTrust Digital Library, 2010. MiAaHDL
Note Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. MiAaHDL
Print version record.
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Subject Tumor markers.
Cancer -- Diagnosis.
Cancer -- Treatment.
Biomarkers, Tumor.
Contents Introduction -- Methods, tools, and resources needed to discover and develop biomarkers -- Guidelines, standards, oversight, and incentives needed for biomarker development -- Methods and process needed for clinical adoption and evaluation of biomarker-based diagnostics.
Summary Many cancer patients are diagnosed at a stage in which the cancer is too far advanced to be cured, and most cancer treatments are effective in only a minority of patients undergoing therapy. Thus, there is tremendous opportunity to improve the outcome for people with cancer by enhancing detection and treatment approaches. Biomarkers will be instrumental in making that transition. Advances in biotechnology and genomics have given scientists new hope that biomarkers can be used to improve cancer screening and detection, to improve the drug development process, and to enhance the effectiveness and safety of cancer care by allowing physicians to tailor treatment for individual patients-an approach known as personalized medicine. However, progress overall has been slow, despite considerable effort and investment, and there are still many challenges and obstacles to overcome before this paradigm shift in oncology can become a reality.
Other Author Nass, Sharyl J.
Moses, Harold L.
Institute of Medicine (U.S.). Committee on Developing Biomarker-Based Tools for Cancer Screening, Diagnosis, and Treatment.
Other Title Print version: Cancer biomarkers. Washington, D.C. : National Academies Press, ©2007 9780309103862