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Title Cancer biomarkers / editor, Alexandros Georgakilas.
Imprint Boca Raton : CRC Press, 2013.


 Internet  Electronic Book    AVAILABLE
Description 1 online resource (xii, 369 pages) : illustrations (some color)
Note "A Science Publishers book."
Bibliog. Includes bibliographical references and index.
Note Available only to authorized UTEP users.
Subject Tumor markers.
Cancer -- Diagnosis.
Biomarkers, Tumor.
Early Detection of Cancer.
Neoplasms -- diagnosis.
Neoplasms -- metabolism.
Neoplastic Processes.
Genre Electronic book.
Contents 1. Improving research on biomarkers for early detection and screening of cancers / Claire S. Zhu, Paul F. Pinsky and Christine D. Berg -- 2. Biomarkers of oxidative stress in carcinogenesis / Humberto Rodriguez-Rocha, Aracely Garcia-Garcia and Rodrigo Franco -- 3. [beta]-catenin : a novel biomarker and therapeutic target in liver cancer / Anupam Bishayee -- 4. Urine biomarkers for prostate cancer detection / Yan-Hua Chen, Art A. Rodriguez and Qun Lu -- 5. Ectodomain shedding as a mechanism to generate cancer biomarkers (ectomarkers) / Maria J. Ruiz-Echevarria, Xiaofei Chen and Ryan F. Overcash -- 6. The BRCT signaling "landscape" : emerging concepts and implications in tumorigenesis and cancer diagnostics / Dimitris Mastellos and George Nounesis -- 7. Cellular senescence and cancer development : antagonistic and synergistic relations / Dimitris Kletsas -- 8. MicroRNAs : from regulators of gene expression to cancer biomarkers / Stamatina Giannouli [and others] -- 9. Targeting PARP-1 in breast cancer : the paradigm of a DNA repair-based therapeutic strategy / Francisco Javier Oliver [and others] -- 10. Statins in prostate cancer : prevention and treatment / Khaled Aziz and Phuoc T. Tran -- 11. Mechanistic aspects of oxidative stress involvement in human environmental and occupational carcinogenesis / Dominique Ziech, Aglaia Pappa and Mihalis I. Panayiotidis.
Summary This unique synthesis of chapters from top experts in their fields, targets the very important and upcoming area of cancer biomarkers and the need for better and more rigorous design and clinical trial. The book covers several aspects of cancer molecular markers from innovation, screening, controversies and future directions. The primary target audience for the book includes PhD and MD students, researchers, biologists, medical doctors and professionals who are interested in mechanistic studies on cancer diagnosis and translational benefits from personalized cancer treatment using the new era of biomarkers.
Other Author Georgakilas, Alexandros.
Other Title 9781578087617