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Title Cysteine proteases of pathogenic organisms / edited by Mark W. Robinson, John P. Dalton.
Imprint New York : Springer Science+Business Media ; Austin, Tex. : Landes Bioscience, ©2011.


 Internet  Electronic Book    AVAILABLE
Description 1 online resource (xix, 226 pages) : illustrations
Series Advances in experimental medicine and biology ; v. 712
Advances in experimental medicine and biology ; v. 712.
Bibliog. Includes bibliographical references and index.
Note Available only to authorized UTEP users.
Print version record.
Subject Cysteine proteinases -- Pathophysiology.
Microbial enzymes.
Pathogenic microorganisms.
Cysteine Proteases -- chemistry.
Bacteria -- enzymology.
Cysteine Proteases -- immunology.
Eukaryota -- enzymology.
Viruses -- enzymology.
biomedische wetenschappen
Medicine (General)
Geneeskunde (algemeen)
Contents Papain-like proteases of staphylococcus aureus -- Lysine specific gingipain of Porphyromonas gingivalis: importance to pathogenicity and potential strategies for inhibition -- Falcipains and other cysteine proteases of malaria parasites -- Cathepsin proteases in Toxoplasma gondii -- Entamoeba Histolytica cathepsin-like enzymes -- Cysteine peptidases of kinetoplastid parasites -- Cruzain: the path from target validation to the clinic -- Phylogeny, structure and function of trematode cysteine proteases, with particular emphasis on the Fasciola hepatica cathepsin L family -- Cathepsins B1 and B2 of Trichobilharzia spp., bird schistosomes causing cercarial dermatitis -- Proteases in blood feeding nematodes and their potential as vaccine candidates -- Cysteine proteases from bloodfeeding arthropod ectoparasites -- How pathogen derived cysteine proteases modulate host immune responses -- Cystatins of parasitic organisms.
Summary Cysteine proteases expressed by pathogenic organisms play key roles in virulence including host entry, feeding and suppression of host immune responses. This book gives comprehensive coverage to all aspects of pathogen cysteine proteases and brings together numerous scientific advances which have been made over many years. Thus, the biochemistry, molecular biology and structure function relationships of these important pathogen enzymes are covered in detail. Written by leading researchers from Europe, Australia and North America, this book is essential reading for students and professionals interested in human medicine and infectious disease research --Provided by publisher.
Other Author Robinson, Mark W. (Mark William), 1977-
Dalton, J. P. (John Pius), 1958-
Other Title Springer eBooks
Print version: Cysteine proteases of pathogenic organisms. New York : Springer Science+Business Media ; Austin, Tex. : Landes Bioscience, ©2011 9781441984135