Limit search to items available for checkout
E-BOOK
Title Systems analysis of human multigene disorders / Natalia Maltsev, Andrey Rzhetsky, T. Conrad Gilliam, editors.
Imprint New York : Springer, 2014.

Copies/Volumes

LOCATION CALL # STATUS
 Internet  Electronic Book    AVAILABLE
Description 1 online resource (134 pages) : illustrations
Series Advances in Experimental Medicine and Biology ; 799
Advances in experimental medicine and biology ; v. 799.
Bibliog. Includes bibliographical references and index.
Note Available only to authorized UTEP users.
Online resource; title from PDF title page (ebrary, viewed January 5, 2014).
Subject Medicine.
Human genetics.
Biological models.
Genetics, Medical -- statistics & numerical data.
Medicine.
Genetics.
Models, Biological.
Contents Wellness and Health Omics Linked to the Environment: The WHOLE Approach to Personalized Medicine / Greg Gibson -- Characterizing Multi-omic Data in Systems Biology / Christopher E. Mason, Sandra G. Porter and Todd M. Smith -- High-Throughput Translational Medicine: Challenges and Solutions / Dinanath Sulakhe, Sandhya Balasubramanian, Bingqing Xie, Eduardo Berrocal, Bo Feng [and 9 others] -- Computational Approaches for Human Disease Gene Prediction and Ranking / Cheng Zhu, Chao Wu, Bruce J. Aronow and Anil G. Jegga -- A Personalized Treatment for Lung Cancer: Molecular Pathways, Targeted Therapies, and Genomic Characterization / Thomas Hensing, Apoorva Chawla, Rishi Batra and Ravi Salgia.
Wellness and Health Omics Linked to the Environment: the WHOLE approach to personalized medicine -- Characterizing Multi-omic Data in Systems Biology -- High-throughput Translational Medicine: Challenges and Solutions -- Computational approaches for human disease gene prediction and ranking -- A Personalized Treatment for Lung Cancer: Molecular Pathways, Targeted Therapies, and Genomic Characterization -- Index.
Summary Understanding the genetic architecture underlying complex multigene disorders is one of the major goals of human genetics in the upcoming decades. Advances in whole genome sequencing and the success of high throughput functional genomics allow supplementing conventional reductionist biology with systems-level approaches to human heredity and health as systems of interacting genetic, epigenetic, and environmental factors. This integrative approach holds the promise of unveiling yet unexplored levels of molecular organization and biological complexity. It may also hold the key to deciphering the multigene patterns of disease inheritance.
Other Author Maltsev, Natalia, editor.
Rzhet︠s︡kiĭ, A. I︠U︡. (Andreĭ I︠U︡rʹevich), editor.
Gilliam, T. Conrad, editor.
Other Title Printed edition: 9781461487777