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Investigational New Drug Application.   4
Investigational New Drug Application -- Periodicals.   1995- 1

Investigational New Drugs -- See Drugs, Investigational

Drugs which have received FDA approval for human testing but have yet to be approved for commercial marketing. This includes drugs used for treatment while they still are undergoing clinical trials (Treatment IND). The main heading includes drugs under investigation in foreign countries.

Investigational Therapies -- See Therapies, Investigational

Treatments which are undergoing clinical trials or for which there is insufficient evidence to determine their effects on health outcomes; coverage for such treatments is often denied by health insurers.
Investigative Techniques   528
Investigative Techniques -- Electronic Journals.   1990- 1
Investigative Techniques -- Periodicals.   1990- 1
Investments.   7
Investments -- analysis.   2007 1
Investments -- legislation & jurisprudence.   2013 1

Involuntary Movements -- See Dyskinesias

Abnormal involuntary movements which primarily affect the extremities, trunk, or jaw that occur as a manifestation of an underlying disease process. Conditions which feature recurrent or persistent episodes of dyskinesia as a primary manifestation of disease may be referred to as dyskinesia syndromes (see MOVEMENT DISORDERS). Dyskinesias are also a relatively common manifestation of BASAL GANGLIA DISEASES.
Involuntary Treatment -- ethics.   2018 1

Iodamoebiasis -- See Amebiasis

Infection with any of various amebae. It is an asymptomatic carrier state in most individuals, but diseases ranging from chronic, mild diarrhea to fulminant dysentery may occur.

Iodination -- See Halogenation

Covalent attachment of HALOGENS to other compounds.
  Iodine -- 2 Related Mesh   2
Iodine.   3
Iodine -- analysis.   2
Iodine -- deficiency.   4
Iodine Isotopes.   1996 1
Iodine -- metabolism.   2009 1
Iodine Radioisotopes -- chemistry.   2006 1
Iodine Radioisotopes -- pharmacokinetics.   1992 1
Iodine Radioisotopes -- therapeutic use.   2006 1
Iodine -- therapeutic use.   1990 1
Iodine -- toxicity.   2004 1

Iodophors -- See Also Anti-Infective Agents, Local

Substances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from DISINFECTANTS, which are used on inanimate objects.
Ion Channel Gating.   2
Ion Channel Gating -- drug effects.   1996 1
Ion Channel Gating -- Periodicals.     1

Ion Channels -- See Also Ion Pumps

A general class of integral membrane proteins that transport ions across a membrane against an electrochemical gradient.
Ion Channels.   28

Ion Channels, Calcium -- See Calcium Channels

Voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. They are categorized as L-, T-, N-, P-, Q-, and R-types based on the activation and inactivation kinetics, ion specificity, and sensitivity to drugs and toxins. The L- and T-types are present throughout the cardiovascular and central nervous systems and the N-, P-, Q-, & R-types are located in neuronal tissue.

Ion Channels, Chloride -- See Chloride Channels

Cell membrane glycoproteins that form channels to selectively pass chloride ions. Nonselective blockers include FENAMATES; ETHACRYNIC ACID; and TAMOXIFEN.
Ion Channels -- Congresses.   c1987 1
Ion Channels -- drug effects.   3
Ion Channels -- genetics.   2
Ion Channels -- genetics [MESH]   1998 1
Ion Channels -- metabolism.   6
Ion Channels -- Periodicals.   3
Ion Channels -- phys   2009 1
Ion Channels -- physiology.   12
Ion Channels -- physiology [MESH]   1998 1
Ion Channels -- physiopathology   2010 1

Ion Channels, Potassium -- See Potassium Channels

Cell membrane glycoproteins that are selectively permeable to potassium ions. At least eight major groups of K channels exist and they are made up of dozens of different subunits.

Ion Channels, Sodium -- See Sodium Channels

Ion channels that specifically allow the passage of SODIUM ions. A variety of specific sodium channel subtypes are involved in serving specialized functions such as neuronal signaling, CARDIAC MUSCLE contraction, and KIDNEY function.
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