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Title Analysis of complex diseases : a mathematical perspective / Guanyu Wang.
Imprint Boca Raton : Taylor & Francis, [2014]


 Internet  Electronic Book    AVAILABLE
Description 1 online resource (228 pages) : illustrations (some color)
Bibliog. Includes bibliographical references.
Note Available only to authorized UTEP users.
Print version record.
Subject Metabolism -- Disorders.
Metabolic Diseases -- complications.
Models, Biological.
Phosphatidylinositol 3-Kinases -- metabolism.
Systems Biology -- methods.
Genre Electronic books.
Contents Food intake and energy metabolism -- Glucose homeostasis -- Optimal glucose homeostasis -- Bistability as a fundamental phenomenon -- Biomolecular network -- P13K-AKT-TOR pathway -- Diseases related to metabolism -- Mathematical modeling of the P13K-AKT-TOR Pathway -- Fundamental decomposition -- Normal phenotype -- Disease phenotypes -- Tao of diseases.
Summary A complex disease involves many etiological and risk factors operating at multiple levels-molecular, cellular, organismal, and environmental. The incidence of such diseases as cancer, obesity, and diabetes are increasing in occurrence, urging us to think fundamentally and use a broader perspective to identify their connection and revolutionize treatments. The understanding of biological data derived from studying diseases can be enhanced by theories and mathematical models, which clarify the big picture and help to reveal the overarching mechanisms that govern complex biological phenomena.
Other Title Print version: Wang, Guanyu. Analysis of complex diseases : a mathematical perspective. Boca Raton : Taylor & Francis, [2014] xxi, 196 pages, 8 unnumbered pages of plates 9781466572218