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Title Protein folding and misfolding : neurodegenerative diseases / edited by Judit Ovdi, Ferenc Orosz.
Imprint Dordrecht ; London : Springer, 2009.


 Internet  Electronic Book    AVAILABLE
Description 1 online resource
Series Focus on structural biology ; 7
Focus on structural biology ; 7.
Bibliog. Includes bibliographical references and index.
Note Available only to authorized UTEP users.
Print version record.
Subject Protein folding.
Proteins -- Denaturation.
Nervous system -- Degeneration -- Pathophysiology.
Proteostasis Deficiencies.
Protein Folding.
Neurodegenerative Diseases.
Metabolic Diseases.
Biophysical Phenomena.
Biochemical Phenomena.
Nervous System Diseases.
Chemical Phenomena.
Nutritional and Metabolic Diseases
Neurodegenerative Diseases -- physiopathology.
Physical Phenomena.
Phenomena and Processes
Contents Structural Disorder and Its Connection with Misfolding Diseases; Intrinsic Disorder in Proteins Associated with Neurodegenerative Diseases; Dynamic Role of Ubiquitination in the Management of Misfolded Proteins Associated with Neurodegenerative Diseases; Protein Misfolding and Axonal Protection in Neurodegenerative Diseases; Endoplasmic Reticulum Stress in Neurodegeneration; Involvement of Alpha-2 Domain in Prion Protein Conformationally-Induced Diseases; Synuclein Structure and Function in Parkinson's Disease.
Summary Reviews the molecular events initiated by unfolded or misfolded proteins leading to conformational human diseases, with special emphasis on the macromolecular homo- and heteroassociations of the malfolded proteins into characteristic ultrastructures found primarily in Parkinson's and Alzheimer's diseases.
Other Author Ovdi, Judit.
Orosz, Ferenc.
Other Title Print version: Protein folding and misfolding. Dordrecht ; London : Springer, 2009 9781402094330 1402094337