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Title Stem cells handbook / Stewart Sell, editor.
Imprint [Totowa, New Jersey] : Humana Press ; New York : Springer, [2013]


 Internet  Electronic Book    AVAILABLE
Edition Second edition.
Description 1 online resource (xvi, 534 pages)
Bibliog. Includes bibliographical references and index.
Note Available only to authorized UTEP users.
Print version record.
Subject Stem cells.
Stem Cells -- physiology.
Contents Introduction to stem cells / Rob Burgess -- Contemporary ethical issues in stem cell research / Valerie Gutmann Koch, Beth E. Roxland, Barbara Pohl and Sarah K. Keech -- Part I. Embryonic/fetal stem cells. Stem cells from early mammalian embryos / Anna-Katerina Hadjantonakis, Svetlana Gavrilov, Panagiotis Xenopoulos, and Virginia E. Papaioannou -- Quantitative approaches to model pluripotency and differentiation in stem cells / Dmitri Papatsenko, Huilei Xu, Avi Ma'ayan, and Ihor Lemischka -- Growth dynamics of fetal human neural stem cells / Walter D. Niles, Dustin R. Wakemann, and Evan Y. Snyder -- Immunobiology of embryonic and induced pluripotent stem cell transplantation / Eleanor M. Bolton, J. Andrew Bradley, and Craig J. Taylor.
Part II. Pluripotent stem cells. Urodele limb regeneration: mechanisms of blastema formation and growth / David L. Stocum -- Mechanism of miR-302-mediated iPS cell generation / Shi-Lung Lin -- Bioreactor expansion of pluripotent stem cells / Jaymi T. Taiani, Mehdi Shafa, and Derrick E. Rancourt -- Generation of hepatocyte-like cells from human pluripotent stem cells / Fallon K. Noto and Stephen A. Duncan -- Neural differentiation from pluripotent stem cells / Mahendra Rao and Nasir Malik -- Generation of anterior foregut derivatives from pluripotent stem cells / Hans-Willem Snœck -- Commercial opportunities for induced pluripotent stem cells / Amy Lynnette Van Deusen and Rania Nasis.
Part III. Tissue stem cells. Spermatogonial stem cells in adult mice and men / Courtney Sachs and Marco Seandel -- Characterization of the hematopoietic stem cell niche: cellular and molecular analysis / Charles Durand, Thomas Häupl, and Pierre Charbord -- Glandular stem cells (GSCs): stem cells in glandular organs / Ming Jiang, Karin Williams, and Simon W. Hayward -- Human mammary epithelial stem/progenitor cells / Patricia J. Keller, Lisa M. Arendt, and Charlotte Kuperwasser -- Mammary epithelial stem cells / Brian W. Booth, Daniel Medina, and Gilbert H. Smith -- Gastric stem cell biology: proliferation kinetics, differentiation hierarchies, and role in carcinogenesis / Sherif M. Karam -- Progenitors of islet cells / Isabelle Houbracken, Josue Kunjom Mfopou, and Luc Bouwens -- Stem cell populations giving rise to liver, biliary tree, and pancreas / Mark E. Furth, Yunfang Wang, Vincenzo Cardinale, Guido Carpino, Giacomo Lanzoni, Cai-Bin Cui, Eliane Wauthier, David Gerber, Tsunekazu Oikawa, Juan Dominguez-Bendala, Luca Inverardi, Domenico Alvaro, Eugenio Gaudio, and Lola M. Reid -- Liver regeneration in health and disease / Malcolm R. Alison and Shariar Islam -- Human-induced pluripotent stem cells, embryonic stem cells, and their cardiomyocyte derivatives: an overview / Shiva Prasad Potta, Tomo Šarić, Michael Heke, and Jürgen Hescheler -- Potential of glial cells / Magdalena Götz and Swetlana Sirko -- Stem cells and aging / Heidi Scrable and Susan Ashrafzadeh-Kian.
Part IV. Stem cell transplantation. Translating stem cell discoveries / Alan Trouson -- Mesenchymal stromal/stem cell transplantation: from tissue regeneration to immune modulation / Peiman Hematti -- Stem cells and tissue engineering in burns and wounds / Patrick H. Blit, Anna I. Arno, and Marc G. Jeschke -- Derivation of retinal pigmented epithelial cells for the treatment of ocular disease / Dennis O. Clegg, Sherry T. Hikita, Qirui Hu, Dave Buchholz, Teisha J. Rowland, Britney Pennington, Roxanne Croze, Lyndsay Leach, Marlene Tsie, Lisa Conti, and Lincoln V. Johnson -- Stem cells and diabetes / Der-I Kao and Shuibing Chen.
Part V. Stem cells and cancer. Cancer is a problem of developmental biology: maturation arrest and the hierarchical model of the origin of cancer from stem cells / Stewart Sell and Pier Mario Biava -- Targeting the stem cell plasticity of tumor cells / Luigi Strizzi, Katharine M. Hardy, Thomas M. Bodenstine, and Mary J.C. Hendrix -- Molecular evolution of leukemia stem cells / Leslie A. Crews and Catriona H.M. Jamieson -- Rodent models for assessing the role of stem cells in liver development, regeneration, and carcinogenesis / Jennifer A. Sanders and Douglas C. Hixson -- Breast cancer stem cells: from theory to therapy / Sarah J. Conley and Max S. Wicha -- Nephroblastoma/Wilms tumor: a corrupted cap stem cell caricature / Michael D. Hall and Alan O. Perantoni.
Summary Stem Cells Handbook, second edition, emphasizesthe advances in understanding and working with embryonic and fetal stem cells as well as induced pluripotent stem cells that show the most promise for clinical use. This new edition has been completely rewritten and updated to reflect the significant advances made in this field since publication of the first edition in 2004. The thirty-six chapters in this book all written by recognized experts in Stem Cell research reflect the tremendous progress in the understanding of stem cell biology and the appreciation of the potential for using stem cells for therapy of cancer, aging, injury and congenital diseases. Arguably the biggest advances have been made in obtaining different populations of stem cells, inducing mature cells to act like stem cells, and the ever-critical issue of how to get these stem cells to expand and differentiate into the tissue precursor cells that then can be used to replace lost of damaged tissues. No less exciting are the recent advances in understanding how stem cells function to maintain tissue integrity and how to use this knowledge to prevent developmental abnormalities. Other key topics discussed include: properties of tissue stem cells, transplantation of stem cells, the stem cell as a target for cancer treatment and prevention.
Other Author Sell, Stewart, 1935- editor.
Other Title Print version: Stem cells handbook 9781461476955